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Below is a sample of information available upon subscribing to the Database. This includes detailed product files that can be visualized by clicking on the products name appearing in the grid.
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Database Sample
Sponsor(s) | Product | Type of product | Mode of action | Viral family | Virus | Status-1 | Status-2 | ||||
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Sanofi (Sanofi Pasteur / Sanofi Aventis / Sanofi Genzyme) (global presence) | Dengvaxia Dengvaxia®; ChimeriVax-Dengue; ChimeriVax Dengue; CYD Dengue; CYD-TDV; CYD TDV |
Vaccine | Vaccine based on Recombinant, viral expression vector | Flaviviridae | Dengue virus (DENV) | Market / Licensed for use | Approved for market in Mexico (Dec. 2015), Philippines (Dec. 2015), Brazil (Dec. 2015), Salvador (Jan. 2016), EU (Dec. 19, 2018), USA (May 2019); Filings for marketing authorization completed in several countries endemic for Dengue Fever virus; See Rema | ||||
Argos Therapeutics (formerly Merix Bioscience; USA) (now called CoImmune, no longer in antivirals) | AGS-004 AGS004; AGS 004; Arcelis |
Vaccine | Other | Retroviridae | HIV-1 (Human Immunodeficiency virus) | Phase II | 2 Phase II trials completed (2011 and 2015); No further development | ||||
GSK (GlaxoSmithKline; Glaxo Wellcome) (global presence) | Retrovir® Zidovudine; Azidothymidine; AZT; BW A509U; Zydowin |
Inhibitor | RT Inhibitor: Nucleoside or Nucleotide (including NRTI, NRTTI and NcRTI Inhibitors) | Retroviridae | HIV-1 (Human Immunodeficiency virus) | Market / Licensed for use | Approved for market in US (Mar. 19, 1987) and other markets | ||||
Pharmacor (acquired by Procyon/Ambrilia Biopharma; Canada) (no longer in operation) | P-1946 P1946; P 1946 |
Inhibitor | Protease Inhibitor (PI) | Retroviridae | HIV-1 (Human Immunodeficiency virus) | Preclinical | Lead compound | ||||
TaiMed Biologics (Taiwan, USA) | Trogarzo™ Ibalizumab; Ibalizumab-uiyk; TNX-355; TNX355; TNX 355; Hu5A8; TMB-355; TMB355; TMB 355 |
Antibodies | Entry and/or Fusion inhibitor (single agent) | Retroviridae | HIV-1 (Human Immunodeficiency virus) | Market / Licensed for use | Orphan Drug status; Fast track status; Breakthrough Therapy Designation (Feb. 2015); Priority Review status granted by FDA (Jun. 2017), and FDA approval for US market granted on Mar. 06, 2018; Approved for EU market (Sep. 26, 2019); See Remarks | ||||
Novartis (global) / Novartis Institutes for BioMedical Research (NIBR) / Novartis Institute for Tropical Diseases (NITD) | Focetria® Focetria® A(H1N1); Focetria A(H1N1); Focetria A/H1N1; Influenza A (H1N1) 2009 Monovalent Vaccine |
Vaccine | Non-recombinant protein (subunit) vaccine | Orthomyxoviridae | Swine Influenza virus | Market / Licensed for use | Approved by EMEA for distribution in EU (Sept. 29, 2009) under control of health authorities and governments; WHO-Prequalification status; No longer available (2015); See Remarks | ||||
Abbott / AbbVie (global presence) | A-837093 A-837,093; A837093; A 837093 |
Inhibitor | RNA Polymerase Inhibitor | Flaviviridae | HCV (Hepatitis C virus) | Preclinical | No further development | ||||
Abbott / AbbVie (global presence) | Paritaprevir Veruprevir; ABT-450; ABT450; ABT 450 |
Inhibitor | Protease Inhibitor (PI) | Flaviviridae | HCV (Hepatitis C virus) | Market / Licensed for use | Approved for market in US (Dec. 2014) and other markets as part of combination therapy called Viekira Pak; See Remarks | ||||
Novavax (USA) (formerly DynCorp) | ResVax™ RSV-F VLP vaccine; RSV vaccine; RSV F-VLP vaccine; RSV F VLP vaccine; RSV F vaccine |
Vaccine | Recombinant protein (subunit) or nanoparticle/VLP vaccine | Pneumoviridae | RSV (Respiratory Syncytial virus) | Phase III | New Phase III initiated after failure of a first Phase III trial, Jan. 2017; Fast track designation granted by FDA (2016); See Remarks | ||||
Johnson & Johnson Innovative Medicine / J&J Innovative Medicine (formerly Janssen Therapeutics) (global presence) | TMC353121 TMC-353121; TMC 353121 |
Inhibitor | Entry and/or Fusion inhibitor (single agent) | Pneumoviridae | RSV (Respiratory Syncytial virus) | Preclinical | No further development of the RSV program (Mar. 2023); See Remarks | ||||
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